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Theoretical Biophysics

Our research group is interested in the fascinating interplay of nano-science,
biology and physics. The focus of the work is on phenomena where the interplay between geometry, structure, function and topology are important.

Geometry of Helices

In a study of DNA we show that the double helix adapt a pitch in agreement with its volume fraction being optimized, i.e. that DNA is close-packed. It is shown that there exist long chiral structures for which the strain-twist coupling vanishes. This type of analysis also reveals the reason for DNA to overwind when stretched.

Geometry of the Nucleosome and of Chromatin

We investigate the intriguing structure of the nucleosome and of the chromatin fiber.

Cold denaturation

We calculate phase diagrams for polymers and investigate the peculiar phenomenon of cold denaturation.